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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VHL All Species: 0
Human Site: S43 Identified Species: 0
UniProt: P40337 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P40337 NP_000542.1 213 24153 S43 E E S G P E E S G P E E L G A
Chimpanzee Pan troglodytes XP_001171363 190 20804 L28 P F A H A H S L R P A I S A S
Rhesus Macaque Macaca mulatta XP_001090152 129 14460
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P40338 181 20751 P27 M E A G R P R P V L R S V N S
Rat Rattus norvegicus Q64259 185 21197 R30 G R P R P V L R S V N S R E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505708 183 20745 W29 T N S S G P F W R F K P L S A
Chicken Gallus gallus XP_414447 166 19213 R12 A A A Q L A L R S A G P C L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074153 175 20424 I19 L P L V R S L I S R I Q V N V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.4 52.5 N.A. N.A. 74.6 76 N.A. 37.5 52.1 N.A. 41.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 59.6 57.2 N.A. N.A. 80.2 81.2 N.A. 52.1 64.7 N.A. 55.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 N.A. N.A. 13.3 6.6 N.A. 20 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 0 N.A. N.A. 33.3 6.6 N.A. 26.6 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 13 38 0 13 13 0 0 0 13 13 0 0 13 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 25 0 0 0 13 13 0 0 0 13 13 0 13 0 % E
% Phe: 0 13 0 0 0 0 13 0 0 13 0 0 0 0 0 % F
% Gly: 13 0 0 25 13 0 0 0 13 0 13 0 0 13 0 % G
% His: 0 0 0 13 0 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 13 13 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % K
% Leu: 13 0 13 0 13 0 38 13 0 13 0 0 25 13 0 % L
% Met: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 0 0 0 0 13 0 0 25 0 % N
% Pro: 13 13 13 0 25 25 0 13 0 25 0 25 0 0 13 % P
% Gln: 0 0 0 13 0 0 0 0 0 0 0 13 0 0 0 % Q
% Arg: 0 13 0 13 25 0 13 25 25 13 13 0 13 0 13 % R
% Ser: 0 0 25 13 0 13 13 13 38 0 0 25 13 13 25 % S
% Thr: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 13 0 13 0 0 13 13 0 0 25 0 13 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _